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Modalities of Left Ventricular Assist Device Optimization 

Modalities of Left Ventricular Assist Device Optimization
Modalities of Left Ventricular Assist Device Optimization

Nikhil Narang

, Gabriel Sayer

, and Nir Uriel

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date: 27 February 2021

Continuous flow left ventricular assist devices (LVADs) are a viable long-term option to the end-stage heart failure patient, with improvements in hemocompatibility seen with newer generation devices. The complex interplay of native myocardial contractility, state of the right ventricle, and presence of aortic insufficiency, among other factors, governs cardiac performance in addition to that from the pump. Deliberate speed adjustments by non-invasive and invasive methods can improve the LVAD hemodynamic profile in a manner tailored to the individual patient. Individualized adjustments in pump parameters by these methods may reduce the longitudinal burden of LVAD-related adverse events.

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