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Frailty: Assessment and Associations with Outcomes 

Frailty: Assessment and Associations with Outcomes
Chapter:
Frailty: Assessment and Associations with Outcomes
Author(s):

Shannon M. Dunlay

DOI:
10.1093/med/9780190909291.003.0003
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date: 28 May 2020

Frailty is a syndrome of decreased physiological reserve in response to stressors, which increases the vulnerability to adverse health outcomes. Although there is no standard reference test for detecting frailty before left ventricular assist device (LVAD) implantation, several screening tools can be helpful. Numerous studies have found that frailty is often present in patients scheduled to receive LVADs and is associated with longer and more complicated post-implant hospitalizations and worse long-term mortality. Contemporary data suggest that frailty is at least partially reversible with LVAD therapy in some individuals. New therapeutic strategies to improve or reverse frailty in patients receiving LVADs are needed.

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