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Small Cavernous Malformation Presenting with Medically Refractory Epilepsy 

Small Cavernous Malformation Presenting with Medically Refractory Epilepsy
Small Cavernous Malformation Presenting with Medically Refractory Epilepsy

John R. Williams

, Gabrielle A. White-Dzuro

, Michael R. Levitt

, and Andrew L. Ko

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date: 11 April 2021

Abstract: Cerebral cavernous malformations are a rare but important cause of medically refractory epilepsy. Although medical management is important in seizure control, surgical resection remains the most effective method of both reducing seizure frequency and eliminating hemorrhage risk. The prognosis for seizure control with resection is excellent. Adjacent hemosiderin-stained brain is resected unless the cortical location is highly eloquent. A key part of the management is the decision as to when to offer surgery. Radiosurgery is generally felt to be an ineffective treatment for cavernous malformations. This chapter discusses the diagnosis, presurgical workup, and operative nuances that should be considered when treating this disease.

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