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Diet, Gut, and Brain: A New Horizon 

Diet, Gut, and Brain: A New Horizon
Chapter:
Diet, Gut, and Brain: A New Horizon
Author(s):

Anthony J. Bazzan

, and Daniel A. Monti

DOI:
10.1093/med/9780190690557.003.0001
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date: 30 March 2020

There is growing data that dietary factors have profound effects on inflammation, the gut microbiome, intestinal permeability, and the blood–brain barrier; all of which impact brain health and psychological well-being. The Western diet in particular is deleterious for both physical and cognitive/emotional health. This occurs primarily by causing inflammation in the gut and an activation of the immune system along with causing impairment in the integrity of the gut lining. This allows many reactive molecules to enter the general circulation and even cross the blood–brain barrier. Recent research advances elucidate that understanding the harmful physiological effects of certain dietary behaviors is as important as knowing the role of critical nutrients for optimal brain health. This chapter reviews current knowledge regarding diet and nutrition in the context of psychiatric disorders and brain health. Information is reviewed regarding the most appropriate dietary and nutrition approaches to support optimum brain health.

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