- Foreword
- Contributors
- 1 General Approach to Pregnancy Care in the Neurologic Patient
- 2 Pregnancy Safety and Termination
- 3 Contraception Options in Neurologic Disease
- 4 Pregnancy Physiology
- 5 Fetal Imaging for the Neurologist
- 6 Prenatal Genetics for Women with Neurology Disease
- 7 Radiation Exposure and Neuroimaging During Pregnancy
- 8 Cognitive Changes in Pregnancy
- 9 Principles of Reproductive Healthcare in Chronic Neurologic Disease
- 10 Immune-mediated Disorders of the Central Nervous System
- 11 Neurologic Infections in Pregnancy
- 12 Headache
- 13 Traumatic Brain Injury and Pregnancy
- 14 Ischemic Stroke Management in Pregnancy
- 15 Hemorrhagic Stroke Management in Pregnancy
- 16 Management of Intracranial Vascular Lesions During Pregnancy
- 17 Cerebral Venous Thrombosis
- 18 Brain Tumors in Pregnancy
- 19 Movement Disorders in Pregnancy
- 20 Pregnancy and Epilepsy
- 21 Seizure Medications Effects on Fetus, Neonate, and Lactation
- 22 Postpartum Care for Women with Epilepsy
- 23 Sleep Disorders and Pregnancy
- 24 Neuromuscular Diseases
- 25 Charcot-Marie-Tooth Disease and Pregnancy
- 26 Guillain-Barré Syndrome and Chronic Inflammatory Demyelinating Polyradiculoneuropathy in Pregnancy
- 27 Entrapment Neuropathy and Pregnancy
- 28 Neurocutaneous Disorders in Pregnancy
- 29 Spinal Cord Injury in Pregnancy
- 30 Inherited Metabolic Diseases (IMDs) and Pregnancy
- 31 Approach to Delivery in the Patient with Neurologic Disease
- 32 Anesthetic Considerations for Neurologic Patients
- 33 Neurologic Complications in Obstetric Anesthesia
- 34 Perinatal Depression in Neurological Disease and Disability
- 35 Breastfeeding in the Context of Neurological Disorders
- Index
(p. 221) Neuromuscular Diseases: Myasthenia Gravis, Spinal Muscular Atrophy, Nondystrophic Myotonias, and Muscular Dystrophies
- Chapter:
- (p. 221) Neuromuscular Diseases: Myasthenia Gravis, Spinal Muscular Atrophy, Nondystrophic Myotonias, and Muscular Dystrophies
- Author(s):
Johanna Hamel
, and Emma Ciafaloni
- DOI:
- 10.1093/med/9780190667351.003.0024
Myasthenia gravis is an acquired autoimmune disorder characterized by weakness of skeletal muscle, which often affects women in the childbearing age. A number of questions arise when a woman with myasthenia gravis plans to become pregnant or presents with pregnancy, as myasthenia can affect the pregnancy, delivery and the fetus. In addition, the pregnancy can affect the course of myasthenia and worsening of the disease during pregnancy may require treatment modifications. Therefore supportive counseling, ideally preceding conception, is indicated, focusing on issues of fertility, treatment optimization and drug safety, risks of worsening of symptoms during pregnancy and delivery. Counseling on possible effects on the infant should be discussed, as such as neonatal myasthenia gravis, a treatable and transient disease. Patients with myasthenia gravis may require more intensive monitoring and care, and should be supported by a multidisciplinary team involving the obstetrician, anesthesiologist, and neurologist.
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- Foreword
- Contributors
- 1 General Approach to Pregnancy Care in the Neurologic Patient
- 2 Pregnancy Safety and Termination
- 3 Contraception Options in Neurologic Disease
- 4 Pregnancy Physiology
- 5 Fetal Imaging for the Neurologist
- 6 Prenatal Genetics for Women with Neurology Disease
- 7 Radiation Exposure and Neuroimaging During Pregnancy
- 8 Cognitive Changes in Pregnancy
- 9 Principles of Reproductive Healthcare in Chronic Neurologic Disease
- 10 Immune-mediated Disorders of the Central Nervous System
- 11 Neurologic Infections in Pregnancy
- 12 Headache
- 13 Traumatic Brain Injury and Pregnancy
- 14 Ischemic Stroke Management in Pregnancy
- 15 Hemorrhagic Stroke Management in Pregnancy
- 16 Management of Intracranial Vascular Lesions During Pregnancy
- 17 Cerebral Venous Thrombosis
- 18 Brain Tumors in Pregnancy
- 19 Movement Disorders in Pregnancy
- 20 Pregnancy and Epilepsy
- 21 Seizure Medications Effects on Fetus, Neonate, and Lactation
- 22 Postpartum Care for Women with Epilepsy
- 23 Sleep Disorders and Pregnancy
- 24 Neuromuscular Diseases
- 25 Charcot-Marie-Tooth Disease and Pregnancy
- 26 Guillain-Barré Syndrome and Chronic Inflammatory Demyelinating Polyradiculoneuropathy in Pregnancy
- 27 Entrapment Neuropathy and Pregnancy
- 28 Neurocutaneous Disorders in Pregnancy
- 29 Spinal Cord Injury in Pregnancy
- 30 Inherited Metabolic Diseases (IMDs) and Pregnancy
- 31 Approach to Delivery in the Patient with Neurologic Disease
- 32 Anesthetic Considerations for Neurologic Patients
- 33 Neurologic Complications in Obstetric Anesthesia
- 34 Perinatal Depression in Neurological Disease and Disability
- 35 Breastfeeding in the Context of Neurological Disorders
- Index