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Cerebral Venous Thrombosis 

Cerebral Venous Thrombosis
Chapter:
Cerebral Venous Thrombosis
Author(s):

Michael R. Pichler

, and Robert D. Brown

DOI:
10.1093/med/9780190667351.003.0017
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date: 05 August 2020

Thrombosis of cortical veins and/or dural venous sinuses (CVT) is a rare but potentially devastating condition. CVT is more common in women and is strongly associated with pregnancy and the postpartum period, likely due to numerous procoagulant changes during this time. CVT can cause a wide range of symptoms depending on location of thrombosis. Clinical manifestations can include headache, cranial nerve deficits, seizures, and venous infarction with associated focal neurologic deficits. Severe cases may progress to coma and death, emphasizing the importance of early diagnosis and treatment. The approach to management of CVT during pregnancy and the postpartum period must be tailored to prevent complications to the mother and child. This chapter addresses the pathogenesis, clinical manifestations, diagnosis, and treatment of CVT in pregnancy and the postpartum period.

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