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Modularity and Modulation of Locomotor Circuits in Adult Vertebrates 

Modularity and Modulation of Locomotor Circuits in Adult Vertebrates
Modularity and Modulation of Locomotor Circuits in Adult Vertebrates

Abdeljabbar El Manira

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date: 18 June 2019

The compartmentalized organization of the nervous system entails that specific functions are localized in different brain areas and regions of the spinal cord. Dedicated microcircuits in each region/area generate relevant motor behaviors by virtue of their connectivity and dynamic computations, combined with their ability to integrate internal and external cues. The patterns of motor actions are often versatile, with continuous change in speed and coordination as circumstances demand. How this versatility is encoded within microcircuits in the brain and spinal cord is a question that has been difficult to address. Although many mechanisms can contribute, two important tenets underlying this versatility are the modularity and modulation of microcircuits.

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