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Methadone Maintenance versus Detoxification and Psychosocial Treatment for Opioid Dependence: The M180 Study 

Methadone Maintenance versus Detoxification and Psychosocial Treatment for Opioid Dependence: The M180 Study
Chapter:
Methadone Maintenance versus Detoxification and Psychosocial Treatment for Opioid Dependence: The M180 Study
Author(s):

Hamilton Hicks

, and Srinivas Muvvala

DOI:
10.1093/med/9780190625085.003.0048
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date: 25 August 2019

This chapter provides a summary of a landmark study on substance use disorders. The study authors tackle a fundamental question in the treatment of opioid dependence. Should patients with opioid dependence be treated with methadone maintenance treatment or prolonged and psychosocially enriched methadone-assisted detoxification? Starting with that question, this chapter describes the basics of the study, including the funding source, study location, who was studied, number of study participants, study design, study interventions, follow-up, study endpoints, results, as well as criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.

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