- Preface
- Contributors
- 1 Smoothing out the Ups and Downs
- 2 “He Wants It All the Time, Doctor”
- 3 Becoming a Little Forgetful
- 4 Beyond Tremor, Slowness, and Stiffness
- 5 Is Now the Time … ?
- 6 When Less Is More
- 7 “Are My Children at Risk, Doctor?”
- 8 “I Am Not Sure If I Should Do DaT”
- 9 Parkinson’s Disease with an Unusual Tremor
- 10 Falling All the Time
- 11 “My Arm Is Not Working”
- 12 “I See Them Sitting on My Bed, Doctor”
- 13 A New Loss of Order
- 14 Falls
- 15 Siblings with Instability
- 16 Parkinson’s Disease or Essential Tremor?
- 17 Seizures and Shakes
- 18 A Tremor with an Abnormal Posture
- 19 Advanced Treatment for Dystonia
- 20 Twists and Turns
- 21 Delayed and Often Persistent
- 22 The Stand-Alone Tremor
- 23 “She Is So Fidgety”
- 24 “I Have Never Seen Anything Like It Before”
- 25 Slow with an Altered Sensorium
- 26 “It Has to Be Functional!”
- 27 Could It Possibly Be … ?
- 28 A Rapidly Progressive Movement Disorder
- 29 Wakeful Unresponsiveness
- 30 An Iatrogenic Catatonia
- 31 Always Worth a Second Look
- Index
(p. 203) A Rapidly Progressive Movement Disorder
- Chapter:
- (p. 203) A Rapidly Progressive Movement Disorder
- Author(s):
Susan H. Fox
and Marina Picillo
- DOI:
- 10.1093/med/9780190607555.003.0028
Prion diseases are a rare group of transmissible and untreatable encephalopathies that ultimately result in death after a short and rapidly progressive illness. The clinical features are variable but share a mix of cortical and subcortical features and a tendency for worsening at a speed that is typically faster than the monthly or yearly change seen in degenerative forms of dementia. Movement disorders represent a prominent feature of prion diseases and include cerebellar and extrapyramidal symptoms. Myoclonus is by far the most common involuntary movement in prion diseases. An awareness of the diagnosis is important to avoid the risk of iatrogenic transmission and to allow a discussion about prognosis with family and relatives.
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- Preface
- Contributors
- 1 Smoothing out the Ups and Downs
- 2 “He Wants It All the Time, Doctor”
- 3 Becoming a Little Forgetful
- 4 Beyond Tremor, Slowness, and Stiffness
- 5 Is Now the Time … ?
- 6 When Less Is More
- 7 “Are My Children at Risk, Doctor?”
- 8 “I Am Not Sure If I Should Do DaT”
- 9 Parkinson’s Disease with an Unusual Tremor
- 10 Falling All the Time
- 11 “My Arm Is Not Working”
- 12 “I See Them Sitting on My Bed, Doctor”
- 13 A New Loss of Order
- 14 Falls
- 15 Siblings with Instability
- 16 Parkinson’s Disease or Essential Tremor?
- 17 Seizures and Shakes
- 18 A Tremor with an Abnormal Posture
- 19 Advanced Treatment for Dystonia
- 20 Twists and Turns
- 21 Delayed and Often Persistent
- 22 The Stand-Alone Tremor
- 23 “She Is So Fidgety”
- 24 “I Have Never Seen Anything Like It Before”
- 25 Slow with an Altered Sensorium
- 26 “It Has to Be Functional!”
- 27 Could It Possibly Be … ?
- 28 A Rapidly Progressive Movement Disorder
- 29 Wakeful Unresponsiveness
- 30 An Iatrogenic Catatonia
- 31 Always Worth a Second Look
- Index
