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Ocular Myasthenia 

Ocular Myasthenia
Chapter:
Ocular Myasthenia
Author(s):

Matthew J. Thurtell

, and Robert L. Tomsak

DOI:
10.1093/med/9780190603953.003.0022
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date: 26 May 2020

Ocular myasthenia typically causes intermittent or fluctuating ptosis and diplopia yet can be difficult to diagnose definitively. In this chapter, we begin by reviewing the symptoms and signs of ocular myasthenia. We next discuss the laboratory workup for antibodies that are associated with ocular myasthenia and describe bedside tests that can helpful for confirming the diagnosis. We then discuss electrophysiology testing that can be helpful, including repetitive nerve stimulation testing and single-fiber electromyography. Lastly we review the management options for ocular myasthenia, which include symptomatic treatments (such as pyridostigmine), immunosuppression (such as corticosteroids and steroid-sparing agents), and surgical treatments (such as eyelid and strabismus surgery).

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