- Target Audience
- Overall Learning Objectives
- Faculty
- Physician Continuing Medical Education
- Pharmacist Continuing Education
- Nursing Continuing Education
- Disclosure of Conflicts of Interest
- Disclosure of Unlabeled Use
- 1. Epidemiology and the Spread of HIV
- 2. The Origin, Evolution, and Epidemiology of HIV-1 and HIV-2
- 3. Mechanisms of HIV Transmission
- 4. HIV Transmission Prevention
- 5. Immunology
- 6. HIV Cure Strategies<sup>a</sup>
- 7. HIV Testing and Counseling
- 8. Laboratory Testing Strategies
- 9. The Medical History and Physical Examination of the HIV-Infected Patient
- 10. Initial Laboratory Evaluation and Risk Stratification of the HIV-Infected Patient
- 11. Clinical Syndromes and Differential Diagnosis in the HIV-Infected Patient
- 12. Health Maintenance
- 13. Issues in Specific Patient Populations
- 14. Complementary and Alternative Medicine/Integrative Medicine Approaches
- 15. Care Coordination
- 16. Palliative Care and End-of-Life Support
- 17. HIV Virology
- 18. Principles of Applied Clinical Pharmacokinetics and Pharmacodynamics in Antiretroviral Therapy
- 19. Classes of Antiretrovirals
- 20. Initiation of Antiretroviral Therapy
- 21. HIV-1 Resistance to Antiretroviral Drugs
- 22. Managing the Patient with Multidrug-Resistant HIV
- 23. Future Antiretrovirals, Immune-Based Strategies, and Therapeutic Vaccines
- 24. The Pharmacist’s Role in Caring for HIV-Positive Individuals
- 25. Solid Organ Transplantation in HIV-Infected Individuals
- 26. Antiretroviral Therapy in Pregnant Women
- 27. Antiretroviral Therapy in Children and Newborns
- 28. Immunosuppressants and Antiretroviral Therapy in HIV-Positive Transplant Patients
- 29. Understanding and Managing Antineoplastic and Antiretroviral Therapy
- 30. Substance Abuse in HIV Populations
- 31. Understanding the Use of Antiretroviral Drugs in the Aging Patient
- 32. Opportunistic Infections
- 33. Malignant Diseases in HIV
- 34. Dermatologic Complications
- 35. Endocrine Disorders
- 36. Non-opportunistic Infections
- 37. Psychiatric Illness and Treatment in HIV Populations
- 38. HIV-Associated Neurocognitive Disorders
- 39. HIV/Hepatitis Co-infection
- 40. Ocular Complications
- 41. Cardiovascular Disease
- 42. Renal Complications
- 43. Musculoskeletal Complications of HIV
- 44. Sexually Transmitted Diseases
- 45. HIV and Bone Health
- 46. HIV-Associated Lipodystrophy and Lipoatrophy
- 47. Dyslipidemia
- 48. Immune Reconstitution Inflammatory Syndrome
- 49. US Health Care Systems, HIV Programs, and Coverage Policy Issues
- 50. Legal Issues<sup>a</sup>
- 51. Research Design and Analysis
- 52. Ethical Conduct of Clinical Trials, Institutional Review Boards, Informed Consent, and Financial Conflicts of Interest
- Index
(p. 351) Malignant Diseases in HIV
- Chapter:
- (p. 351) Malignant Diseases in HIV
- Author(s):
Nora Oliver
and Elizabeth Chiao
- DOI:
- 10.1093/med/9780190493097.003.0033
Malignancies were one of the earliest recognized manifestations that led to the eventual description of the AIDS epidemic. Kaposi’s sarcoma was one of the first entities described in association with AIDS. Subsequently, intermediate-grade and high-grade non-Hodgkin’s lymphoma, invasive cervical cancer, and primary central nervous system lymphoma were defined by the Centers for Disease Control and Prevention as “AIDS-defining conditions.” Since the advent of combination antiretroviral therapy, several other cancers that are not AIDS-defining have been found to have an increased incidence in patients with HIV. These include, but are not limited to, Hodgkin’s disease and anal, liver, lung, oropharyngeal, colorectal, and renal cancers. They are generally referred to as “non-AIDS-defining cancers.” The increasing longevity of persons living with HIV as well as concurrent modifiable risk factors such as tobacco use may also influence the epidemiology of these malignancies.
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- Target Audience
- Overall Learning Objectives
- Faculty
- Physician Continuing Medical Education
- Pharmacist Continuing Education
- Nursing Continuing Education
- Disclosure of Conflicts of Interest
- Disclosure of Unlabeled Use
- 1. Epidemiology and the Spread of HIV
- 2. The Origin, Evolution, and Epidemiology of HIV-1 and HIV-2
- 3. Mechanisms of HIV Transmission
- 4. HIV Transmission Prevention
- 5. Immunology
- 6. HIV Cure Strategies<sup>a</sup>
- 7. HIV Testing and Counseling
- 8. Laboratory Testing Strategies
- 9. The Medical History and Physical Examination of the HIV-Infected Patient
- 10. Initial Laboratory Evaluation and Risk Stratification of the HIV-Infected Patient
- 11. Clinical Syndromes and Differential Diagnosis in the HIV-Infected Patient
- 12. Health Maintenance
- 13. Issues in Specific Patient Populations
- 14. Complementary and Alternative Medicine/Integrative Medicine Approaches
- 15. Care Coordination
- 16. Palliative Care and End-of-Life Support
- 17. HIV Virology
- 18. Principles of Applied Clinical Pharmacokinetics and Pharmacodynamics in Antiretroviral Therapy
- 19. Classes of Antiretrovirals
- 20. Initiation of Antiretroviral Therapy
- 21. HIV-1 Resistance to Antiretroviral Drugs
- 22. Managing the Patient with Multidrug-Resistant HIV
- 23. Future Antiretrovirals, Immune-Based Strategies, and Therapeutic Vaccines
- 24. The Pharmacist’s Role in Caring for HIV-Positive Individuals
- 25. Solid Organ Transplantation in HIV-Infected Individuals
- 26. Antiretroviral Therapy in Pregnant Women
- 27. Antiretroviral Therapy in Children and Newborns
- 28. Immunosuppressants and Antiretroviral Therapy in HIV-Positive Transplant Patients
- 29. Understanding and Managing Antineoplastic and Antiretroviral Therapy
- 30. Substance Abuse in HIV Populations
- 31. Understanding the Use of Antiretroviral Drugs in the Aging Patient
- 32. Opportunistic Infections
- 33. Malignant Diseases in HIV
- 34. Dermatologic Complications
- 35. Endocrine Disorders
- 36. Non-opportunistic Infections
- 37. Psychiatric Illness and Treatment in HIV Populations
- 38. HIV-Associated Neurocognitive Disorders
- 39. HIV/Hepatitis Co-infection
- 40. Ocular Complications
- 41. Cardiovascular Disease
- 42. Renal Complications
- 43. Musculoskeletal Complications of HIV
- 44. Sexually Transmitted Diseases
- 45. HIV and Bone Health
- 46. HIV-Associated Lipodystrophy and Lipoatrophy
- 47. Dyslipidemia
- 48. Immune Reconstitution Inflammatory Syndrome
- 49. US Health Care Systems, HIV Programs, and Coverage Policy Issues
- 50. Legal Issues<sup>a</sup>
- 51. Research Design and Analysis
- 52. Ethical Conduct of Clinical Trials, Institutional Review Boards, Informed Consent, and Financial Conflicts of Interest
- Index