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Solid Organ Transplantation in HIV-Infected Individuals 

Solid Organ Transplantation in HIV-Infected Individuals
Chapter:
Solid Organ Transplantation in HIV-Infected Individuals
Author(s):

Eurides Lopes

and Jennifer Husson

DOI:
10.1093/med/9780190493097.003.0025
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date: 27 October 2020

End-organ disease has become a major cause of morbidity and mortality in HIV-infected patients due to increased life expectancy, increasing the demand for organ transplantation in these patients. The care of HIV-infected transplant recipients warrants a multidisciplinary team approach, including the transplant team, pharmacists, infectious disease specialists, nurses, and patients and their families. The immunosuppression of HIV-infected recipients post-transplant does not appear to further advance HIV disease. The post-transplant risk for HIV-infected recipients of opportunistic infections does not appear to be increased by immunosuppression. However, the overall rate of infections is high, and it is even higher in hepatitis C virus (HCV) co-infected transplant recipients. HIV/HCV co-infected recipients have worse outcomes compared to both liver and kidney HIV-infected recipients.

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