- Dedication
- Preface
- Acknowledgments
- 1 A 35-Year-Old Man with Progressive Left-Hand Weakness
- 2 A 54-Year-Old Male with Right-Hand Weakness
- 3 A 50-Year-Old Male with Speech, Swallowing, and Behavioral Difficulties
- 4 A 45-Year-Old Male with Toxin Exposure
- 5 A 48-Year-Old with Progressive Weakness and Pain
- 6 A 30-Year-Old Male Requiring Management of Progressive Weakness
- 7 A 61-Year-Old Male with Severe Shoulder and Cervical Pain
- 8 A 55-Year-Old Male with Right Foot Weakness
- 9 A 63-Year-Old Male with Severe Flaccid Weakness Post Motor Vehicle Accident
- 10 A 55-Year-Old Female with Slowly Progressive Weakness
- 11 A 40-Year-Old Female with Balance Problems and Numbness After Bariatric Surgery
- 12 A 55-Year-Old Female with a History of Right Foot Drop and Left Hand Weakness
- 13 A 40-Year-Old Female with Increasing Arm Pain and Numbness
- 14 A 59-Year-Old Man with Progressive Difficulties with Balance and Weight Loss
- 15 A 68-Year-Old Male with Progressive Numbness and Gait Difficulties
- 16 A 28-Year-Old Male with Weakness in the Setting of Cancer
- 17 A 44-Year-Old Man with Bilateral Facial Droop
- 18 A 41-Year-Old Male with Foot Drop and Malaise
- 19 A 44-Year-Old Female with Buttock Pain
- 20 A 50-Year-Old Woman with Burning Feet
- 21 A 56-Year-Old Woman with Small-Fiber Neuropathy and Progressive Leg Pain and Weakness
- 22 A 34-Year-Old Male with Possible Myopathic Process
- 23 A 39-Year-Old Man with Low Back Pain and Scapular Winging
- 24 A 52-Year-Old Female with Weakness and Droopy Eyelids
- 25 A 20-year-Old Male with Acute Lower-Extremity Weakness
- 26 A 19-Year-Old Male with Stiffness and Weakness After Waking
- 27 A 68-Year-Old Female with Progressive Pain and Weakness
- 28 An 18-Year-Old Male with Slowly Progressive Weakness
- 29 A 30-Year-Old Male with Severe Cramps
- 30 A 72-Year-Old Female with Facial Weakness and Droopy Eyelids
- 31 An 80-Year-Old Myasthenia Gravis Patient with Worsening Weakness
- 32 A 44-Year-Old Male with Subacute Onset of Syncope
- 33 A 46-Year-Old Man with Double Vision and Proximal Leg Weakness
- 34 A 2-Month-Old Boy with Acute Diffuse Weakness
- Index
(p. 27) A 48-Year-Old with Progressive Weakness and Pain
- Chapter:
- (p. 27) A 48-Year-Old with Progressive Weakness and Pain
- Author(s):
Jeffrey A. Cohen
, Justin J. Mowchun
, Victoria H. Lawson
, and Nathaniel M. Robbins
- DOI:
- 10.1093/med/9780190491901.003.0005
Guillain-Barré syndrome may present in several ways, although predominant proximal weakness is a common feature of the disease to recognize. The differential diagnosis may be extensive and can include infection, vasculitis, toxin exposure, and malignancy. A lumbar puncture must be done with minimal delay to evaluate for cerebrospinal fluid (CSF) albuminocytological dissociation, however results may be normal early in the course of the disease. EMG/NCS are helpful to support the diagnosis, and early treatment with intravenous immunoglobulin (IVIG) is essential. This chapter discusses the clinical features and diagnostic considerations of this important condition.
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- Dedication
- Preface
- Acknowledgments
- 1 A 35-Year-Old Man with Progressive Left-Hand Weakness
- 2 A 54-Year-Old Male with Right-Hand Weakness
- 3 A 50-Year-Old Male with Speech, Swallowing, and Behavioral Difficulties
- 4 A 45-Year-Old Male with Toxin Exposure
- 5 A 48-Year-Old with Progressive Weakness and Pain
- 6 A 30-Year-Old Male Requiring Management of Progressive Weakness
- 7 A 61-Year-Old Male with Severe Shoulder and Cervical Pain
- 8 A 55-Year-Old Male with Right Foot Weakness
- 9 A 63-Year-Old Male with Severe Flaccid Weakness Post Motor Vehicle Accident
- 10 A 55-Year-Old Female with Slowly Progressive Weakness
- 11 A 40-Year-Old Female with Balance Problems and Numbness After Bariatric Surgery
- 12 A 55-Year-Old Female with a History of Right Foot Drop and Left Hand Weakness
- 13 A 40-Year-Old Female with Increasing Arm Pain and Numbness
- 14 A 59-Year-Old Man with Progressive Difficulties with Balance and Weight Loss
- 15 A 68-Year-Old Male with Progressive Numbness and Gait Difficulties
- 16 A 28-Year-Old Male with Weakness in the Setting of Cancer
- 17 A 44-Year-Old Man with Bilateral Facial Droop
- 18 A 41-Year-Old Male with Foot Drop and Malaise
- 19 A 44-Year-Old Female with Buttock Pain
- 20 A 50-Year-Old Woman with Burning Feet
- 21 A 56-Year-Old Woman with Small-Fiber Neuropathy and Progressive Leg Pain and Weakness
- 22 A 34-Year-Old Male with Possible Myopathic Process
- 23 A 39-Year-Old Man with Low Back Pain and Scapular Winging
- 24 A 52-Year-Old Female with Weakness and Droopy Eyelids
- 25 A 20-year-Old Male with Acute Lower-Extremity Weakness
- 26 A 19-Year-Old Male with Stiffness and Weakness After Waking
- 27 A 68-Year-Old Female with Progressive Pain and Weakness
- 28 An 18-Year-Old Male with Slowly Progressive Weakness
- 29 A 30-Year-Old Male with Severe Cramps
- 30 A 72-Year-Old Female with Facial Weakness and Droopy Eyelids
- 31 An 80-Year-Old Myasthenia Gravis Patient with Worsening Weakness
- 32 A 44-Year-Old Male with Subacute Onset of Syncope
- 33 A 46-Year-Old Man with Double Vision and Proximal Leg Weakness
- 34 A 2-Month-Old Boy with Acute Diffuse Weakness
- Index