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Interstitial Lung Diseases 

Interstitial Lung Diseases
Interstitial Lung Diseases

Fabien Maldonado

and Timothy R. Aksamit

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date: 19 October 2019

Cystic fibrosis (CF) is the most common autosomal recessive disease among whites, with a frequency of 1 in 2,000 to 1 in 3,000 live births. The disease is caused by a mutation in the gene that encodes for the CF transmembrane conductance regulator on chromosome 7. This mutation causes production of thick, sticky secretions that clog the airways and the pancreatic and biliary ducts, resulting in chronic cough, frequent sinus and lower respiratory tract infections, progressive bronchiectasis, end-stage lung disease, pancreatic insufficiency, diabetes mellitus, biliary disease, and malabsorption.

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