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HIV Infectiona 

HIV Infectiona
Chapter:
HIV Infectiona
Author(s):

Mary J. Kasten

and Zelalem Temesgen

DOI:
10.1093/med/9780190464868.003.0042
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date: 19 October 2019

Acute bacterial meningitis is an infectious disease emergency. The incidence of bacterial meningitis is estimated to be 3.0 cases per 100,000 person-years, and its overall case fatality rate is 25% in adults. Common predisposing conditions for community-acquired meningitis include acute otitis media, altered immune states, alcoholism, pneumonia, diabetes mellitus, sinusitis, and a cerebrospinal fluid leak. Risk factors for death among adults with community-acquired meningitis include age 60 years or older, altered mental status at presentation, pneumococcal cause, and occurrence of seizures within 24 hours of symptom onset.

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