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Obesity and Nutritional Disorders 

Obesity and Nutritional Disorders
Chapter:
Obesity and Nutritional Disorders
Author(s):

Ryan T. Hurt

DOI:
10.1093/med/9780190464868.003.0016
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date: 19 October 2019

The prevalence of overweight and obesity has been increasing in the United States and the westernized world. The cause of the recent obesity epidemic involves a complex interplay between genetic and environmental factors. Specific, rare genetic disruptions of the hypothalamic regulation of energy homeostasis pathways can cause obesity (eg, Prader-Willi syndrome). Most cases of obesity result from a group of gene variants exposed to environmental factors. The 2 major environmental factors that contribute to overweight and obesity are excess caloric intake and low physical activity.

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