- Case 1 Dyspnea and Edema
- Case 2 An Electrical Problem
- Case 3 Hypertension
- Case 4 A Rare Cause of Liver Failure
- Case 5 Shortness of Breath
- Case 6 Acute Respiratory Failure in a Young Smoker
- Case 7 Shock
- Case 8 Diffuse Abdominal Pain in a 45-Year-Old Woman
- Case 9 An Over-the-Counter Intoxication
- Case 10 An Over-the-Counter Overdose
- Case 11 A Post–Myocardial Infarction Complication
- Case 12 Massive Hemoptysis
- Case 13 Hypotension Following a Broken Hip
- Case 14 Extubation Failure
- Case 15 Hypotension and Right-Sided Heart Failure After Left Pneumonectomy
- Case 16 More Than Meets the Eye
- Case 17 Reverse Apical Ballooning Syndrome Due to Clonidine Withdrawal
- Case 18 A Well-Known Cardiac Condition With a Unique Presentation
- Case 19 Electrolyte Abnormalities During Continuous Renal Replacement Therapy
- Case 20 A Disease Masquerading as Septic Shock
- Case 21 A Respiratory Infection
- Case 22 Infection in a Patient With Chronic Myeloid Leukemia
- Case 23 Torsades de Pointes
- Case 24 The Kidneys Can See When the Eyes Cannot
- Case 25 An Upper Airway Crisis
- Case 26 An Endocrine Emergency
- Case 27 Acute Renal Failure
- Case 28 Hypoxia and Diffuse Pulmonary Infiltrates in an Immunosuppressed Patient With Vasculitis
- Case 29 A Paraneoplastic Syndrome
- Case 30 Complicated Diarrheal Illness
- Case 31 Persistent Shock With Hemorrhagic Complications
- Case 32 An Unusual Presentation of Disseminated Histoplasmosis
- Case 33 Complications of Cirrhosis
- Case 34 A Curious Case of Abdominal Pain
- Case 35 Weakness in the Intensive Care Unit
- Case 36 Altered Mental Status and Rigidity
- Case 37 Overdose
- Case 38 An Unusual Encephalopathy
- Case 39 Brain Death
- Case 40 Use of Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome
- Case 41 Chest Pain and Respiratory Distress
- Case 42 Portal Venous Gas
- Case 43 Acute Respiratory Failure in a Stem Cell Transplant Patient
- Case 44 Flail Chest
- Case 45 Coma
- Case 46 A Bleeding Disorder
- Case 47 A Cardiopulmonary Resuscitation Complication
- Case 48 Severe Influenza A–Associated Acute Respiratory Distress Syndrome
- Case 49 Severe Chest Pain
- Case 50 A More Frequent Airway Emergency
(p. 170) Overdose
- Chapter:
- (p. 170) Overdose
- Author(s):
Arjun Gupta
and Sahil Khanna
- DOI:
- 10.1093/med/9780190464813.003.0037
Acetaminophen overdose is the most common medication poisoning reported to US poison control centers and is the most common cause of acute liver failure in the western world. Acetaminophen is a component of several over-the-counter and prescription medications. Overdose can be intentional or accidental, and it should be considered in the differential diagnosis of markedly elevated liver enzymes. Management includes early recognition, supportive management, removal of unabsorbed medication, prompt antidote administration, and referral to a liver transplant center.
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- Case 1 Dyspnea and Edema
- Case 2 An Electrical Problem
- Case 3 Hypertension
- Case 4 A Rare Cause of Liver Failure
- Case 5 Shortness of Breath
- Case 6 Acute Respiratory Failure in a Young Smoker
- Case 7 Shock
- Case 8 Diffuse Abdominal Pain in a 45-Year-Old Woman
- Case 9 An Over-the-Counter Intoxication
- Case 10 An Over-the-Counter Overdose
- Case 11 A Post–Myocardial Infarction Complication
- Case 12 Massive Hemoptysis
- Case 13 Hypotension Following a Broken Hip
- Case 14 Extubation Failure
- Case 15 Hypotension and Right-Sided Heart Failure After Left Pneumonectomy
- Case 16 More Than Meets the Eye
- Case 17 Reverse Apical Ballooning Syndrome Due to Clonidine Withdrawal
- Case 18 A Well-Known Cardiac Condition With a Unique Presentation
- Case 19 Electrolyte Abnormalities During Continuous Renal Replacement Therapy
- Case 20 A Disease Masquerading as Septic Shock
- Case 21 A Respiratory Infection
- Case 22 Infection in a Patient With Chronic Myeloid Leukemia
- Case 23 Torsades de Pointes
- Case 24 The Kidneys Can See When the Eyes Cannot
- Case 25 An Upper Airway Crisis
- Case 26 An Endocrine Emergency
- Case 27 Acute Renal Failure
- Case 28 Hypoxia and Diffuse Pulmonary Infiltrates in an Immunosuppressed Patient With Vasculitis
- Case 29 A Paraneoplastic Syndrome
- Case 30 Complicated Diarrheal Illness
- Case 31 Persistent Shock With Hemorrhagic Complications
- Case 32 An Unusual Presentation of Disseminated Histoplasmosis
- Case 33 Complications of Cirrhosis
- Case 34 A Curious Case of Abdominal Pain
- Case 35 Weakness in the Intensive Care Unit
- Case 36 Altered Mental Status and Rigidity
- Case 37 Overdose
- Case 38 An Unusual Encephalopathy
- Case 39 Brain Death
- Case 40 Use of Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome
- Case 41 Chest Pain and Respiratory Distress
- Case 42 Portal Venous Gas
- Case 43 Acute Respiratory Failure in a Stem Cell Transplant Patient
- Case 44 Flail Chest
- Case 45 Coma
- Case 46 A Bleeding Disorder
- Case 47 A Cardiopulmonary Resuscitation Complication
- Case 48 Severe Influenza A–Associated Acute Respiratory Distress Syndrome
- Case 49 Severe Chest Pain
- Case 50 A More Frequent Airway Emergency