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Complicated Diarrheal Illness 

Complicated Diarrheal Illness
Complicated Diarrheal Illness

Arjun Gupta

and Sahil Khanna

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date: 18 June 2021

Clostridium difficile infection (CDI) is the most common cause of infectious diarrhea in hospitalized patients and has surpassed methicillin-resistant Staphylococcus aureus as the most common cause of nosocomial infection. CDI is being identified increasingly in community patients without prior hospitalization or antibiotic exposure. Traditional risk factors include older age, antibiotic exposure, and hospitalization; newer risk factors are being identified, although the role of gastric acid suppression is still controversial. Treatment recommendations for CDI are based on severity, and patients with severe or severe-complicated CDI should receive aggressive therapy to prevent adverse outcomes.

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