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An Endocrine Emergency 

An Endocrine Emergency
An Endocrine Emergency

W. Brian Beam

and Ognjen Gajic

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date: 28 January 2021

Diabetic ketoacidosis is the most common diabetes-related complication leading to ICU admission. This metabolic complication is triggered by a marked insulin deficiency along with elevated levels of counter-regulatory hormones. The result is an inability of insulin-sensitive tissues to use glucose, with accelerated gluconeogenesis and glycogenolysis followed by ketoacidosis. Hallmarks of the disorder include hyperglycemia, ketonemia, and an anion gap metabolic acidosis.

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