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Pain Management for General Surgery: Acetaminophen, NSAIDS, and COX-2 Selective Inhibitors Update 

Pain Management for General Surgery: Acetaminophen, NSAIDS, and COX-2 Selective Inhibitors Update
Chapter:
Pain Management for General Surgery: Acetaminophen, NSAIDS, and COX-2 Selective Inhibitors Update
Author(s):

Katherine Stammen

, Harish Siddaiah

, Cody Brechtel

, Elyse M. Cornett

, Charles J. Fox III

, and Alan D. Kaye

DOI:
10.1093/med/9780190457006.003.0006
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date: 01 December 2020

Pain is multidimensional and subjective, which makes it difficult to treat. Newer treatment modalities have been under development with a better understanding of pain pathways in recent years. These treatments take advantage of the multifactorial components of pain, including agents such as ketamine, capsaicin, gabapentin, pregabalin, long-acting opioids, peripheral nerve blockade, and patient-controlled analgesia. Numerous studies have revealed not only efficacy but additive and/or synergistic effects when multiple agents are utilized for pain management. Overall, adequate perioperative pain control is important both in an acute setting and in preventing the development of a chronic pain condition, which causes significant short- and long-term negative consequences. Best practice strategies are being utilized based on clinical studies to reduce pain and improve patient needs after surgery.

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