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Bleeding Disorders, the Coagulation Cascade, and Anticoagulants 

Bleeding Disorders, the Coagulation Cascade, and Anticoagulants
Bleeding Disorders, the Coagulation Cascade, and Anticoagulants

Derek Khorsand

, Bethany Samuelson

, and Christopher Ingraham

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date: 19 September 2020

An understanding of the coagulation cascade, bleeding disorders, and anticoagulants is essential to any interventional radiology (IR) practice. IR patients are frequently critically ill and may suffer from coagulopathy, thrombocytopenia, or both. Furthermore, many IR patients present acutely or electively while on one of many commercially available anticoagulants. Knowledge of the coagulation cascade and an understanding of the hemostatic mechanisms of the body and the use of anticoagulants are essential to allow interventional radiologists to guide strategies in minimizing bleeding and bleeding risk in the IR patient. This chapter presents much of the necessary background information on hemostatis, thrombosis, and the coagulation cascade.

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