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Secondary Liver Tumors 

Secondary Liver Tumors
Chapter:
Secondary Liver Tumors
Author(s):

Samuel L. Rice

, David C. Madoff

, and Stephen B. Solomon

DOI:
10.1093/med/9780190276249.003.0036
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date: 18 October 2019

Metastatic spread of primary neoplasms to the liver is a poor prognostic factor in oncology. It is associated with a diminished overall survival (OS) rate, with most patients living only 1–2 years after tumors are identified. Systemic chemotherapy is the mainstay of treatment for patients with secondary tumors to the liver. An urgent need exists for the development and utilization of novel therapies to improve survival in these patients. Minimally invasive therapies exist that target hepatic tumors and can work synergistically with the systemic treatments currently available to prolong survival. Interventional radiologists have developed and utilized various liver-directed therapies, including embolization and ablation, to improve patient survival. Given the data that is available, these treatments are underutilized by clinicians due to a lack of knowledge about the potential advantages. This chapter discusses the factors related to treating secondary neoplasms in the liver and reviews the evidence supporting these therapies.

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