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Primary Liver Tumors 

Primary Liver Tumors
Chapter:
Primary Liver Tumors
Author(s):

Samuel L. Rice

, Stephen B. Solomon

, and David C. Madoff

DOI:
10.1093/med/9780190276249.003.0035
Page of

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date: 19 September 2019

Primary liver tumors result in substantial morbidity and mortality. Unfortunately, the majority of these tumors are discovered when the disease has progressed beyond the possibility of a curative surgical intervention. Over the past few decades, minimally invasive transcatheter and percutaneous techniques have been developed that offer patients with primary liver tumors extended survival, improved quality of life, and even potentially curative treatment. These therapies comprise procedures that embolize and locally deliver chemotherapy or radioactivity to these tumors or apply thermal or nonthermal ablative techniques that can be performed via a percutaneous approach utilizing computed tomography (CT), ultrasound, or magnetic resonance imaging (MRI) to kill tumor cells directly, with achievement of an appropriative therapeutic margin. This chapter focuses on the workup and clinical management of patients with primary liver cancer; hepatocellular carcinoma (HCC), and cholangiocarcinoma, as well as the role that these aforementioned interventional oncologic techniques have in treating these neoplasms.

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