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Inherited Leukoencephalopathiesa 

Inherited Leukoencephalopathiesa
Chapter:
Inherited Leukoencephalopathiesa
Author(s):

Deborah L. Renaud

DOI:
10.1093/med/9780190244927.003.0086
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date: 23 October 2019

Leukoencephalopathies are disorders that selectively involve the white matter of the brain. Acquired causes of leukoencephalopathy include inflammatory, infectious, vascular, neoplastic, and toxic disorders. Hereditary leukoencephalopathies encompass those conditions that demonstrate progressive destruction or loss of previously acquired central myelin (leukodystrophies) as well as those conditions associated with impaired formation of myelin (dysmyelination or hypomyelination).

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