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Paraneoplastic and Other Autoimmune Neurologic Disorders 

Paraneoplastic and Other Autoimmune Neurologic Disorders
Chapter:
Paraneoplastic and Other Autoimmune Neurologic Disorders
Author(s):

Andrew McKeon

DOI:
10.1093/med/9780190244927.003.0071
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date: 27 February 2021

A paraneoplastic disorder occurs because of the remote effects of malignancy, rather than because of direct tumor invasion. Paraneoplastic neurologic disorders come about because of vigorous immune responses directed against antigens expressed in tumors. The vigor of the immune response usually ensures that neoplasm is confined to the primary organ and regional lymph nodes. The neurologic presentation is often the first clue to the existence, or recurrence, of cancer.

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