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Metastatic Disease 

Metastatic Disease
Metastatic Disease

Alyx B. Porter

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date: 28 September 2021

Intracranial metastases are the most common brain tumors in adults and outnumber primary brain tumors by 10 to 1. These metastases have become the most common neurologic complication of cancer. Intracranial metastases are occurring with increased frequency as a result of improved therapies for systemic cancers. Most patients with brain metastases have lung cancer as the primary malignancy, followed in frequency by breast, melanoma, renal cell, and thyroid cancers. The prognosis when brain metastases are detected varies on the basis of the underlying cancer type. This chapter reviews the approach and management of brain and spinal cord metastases.

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