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Nondegenerative Dementias and Encephalopathies 

Nondegenerative Dementias and Encephalopathies
Nondegenerative Dementias and Encephalopathies

Eoin P. Flanagan

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date: 25 July 2021

The differential diagnosis of dementia is discussed elsewhere. Nondegenerative dementias are a diverse but important group of cognitive disorders because they may be reversible with treatment. Thus, it is important to evaluate for such when suspected. Many of the causes of nondegenerative dementia result in what is known as a subcortical dementia. Subcortical dementia is thought to be primarily due to damage to the frontal subcortical connections, and typical clinical features include inattention, bradyphrenia (slowed thought process), executive dysfunction (difficulties planning and sequencing tasks), apathy, psychomotor slowing, and mood disorders. Gait apraxia and urinary difficulties may coexist. Cortical features such as agnosia, seizures, aphasia, and ideomotor apraxia are typically absent.

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