- Preface
- Introduction
- Part One Main Features of Structure and Function
- 1 Structure of the Neuron and Organization of Nervous Tissue
- 2 Glia
- 3 Neuronal Excitability
- 4 Synaptic Function
- 5 Neurotransmitters and Their Receptors
- 6 Parts of the Nervous System
- 7 The Coverings of the Brain and the Ventricular System
- 8 The Blood Supply of the CNS
- Part Two Development, Aging, and Plasticity
- 9 Prenatal and Postnatal Development
- 10 The Nervous System and Aging
- 11 Restitution of Function after Brain Damage
- Part Three Sensory Systems
- 12 Sensory Receptors in General
- 13 Peripheral Parts of the Somatosensory System
- 14 Central Parts of the Somatosensory System
- 15 Pain
- 16 The Visual System
- 17 The Auditory System
- 18 The Sense of Equilibrium
- 19 Olfaction and Taste
- Part Four Motor Systems
- 20 Motor Systems and Movements in General
- 21 The Peripheral Motor Neurons and Reflexes
- 22 The Motor Cortical Areas and Descending Pathways
- 23 The Basal Ganglia
- 24 The Cerebellum
- 25 Control of Eye Movements
- Part Five The Brain Stem and the Cranial Nerves
- 26 The Reticular Formation: Premotor Networks, Consciousness, and Sleep
- 27 The Cranial Nerves
- Part Six The Autonomic Nervous System
- 28 Visceral Efferent Neurons: The Sympathetic and Parasympathetic Divisions
- 29 Sensory Visceral Neurons and Visceral Reflexes
- 30 The Central Autonomic System: The Hypothalamus
- Part Seven Limbic Structures
- 31 The Amygdala and Other Neuronal Groups with Relation to Emotions
- 32 The Hippocampal Formation: Learning and Memory
- Part Eight The Cerebral Cortex
- 33 The Cerebral Cortex: Intrinsic Organization and Connections
- 34 Functions of the Neocortex
- Literature
- Index
(p. 545) The Hippocampal Formation: Learning and Memory
- Chapter:
- (p. 545) The Hippocampal Formation: Learning and Memory
- Author(s):
Per Brodal
- DOI:
- 10.1093/med/9780190228958.003.0032
Chapter 32 deals with the hippocampus and nearby areas in the parahippocampal gyrus (the dentate gyrus and the entorhinal area), together comprising the hippocampal formation. These structures play a crucial role for certain kinds of learning and memory. The hippocampal formation receives highly processed sensory information, and the hippocampal projection neurons send signals to several cortical areas and to the mammillary nucleus. Only the memory of events and facts (declarative memory) depends critically on the integrity of medial parts of the temporal lobe. The hippocampal formation is not the only part of the brain that is important for memory, however, and it appears to be important only for a certain time after an event. This is probably because, after a certain time, relevant synaptic changes are distributed in many parts of the cerebral cortex. Bilateral damage of the hippocampal formation leads to amnesia.
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- Preface
- Introduction
- Part One Main Features of Structure and Function
- 1 Structure of the Neuron and Organization of Nervous Tissue
- 2 Glia
- 3 Neuronal Excitability
- 4 Synaptic Function
- 5 Neurotransmitters and Their Receptors
- 6 Parts of the Nervous System
- 7 The Coverings of the Brain and the Ventricular System
- 8 The Blood Supply of the CNS
- Part Two Development, Aging, and Plasticity
- 9 Prenatal and Postnatal Development
- 10 The Nervous System and Aging
- 11 Restitution of Function after Brain Damage
- Part Three Sensory Systems
- 12 Sensory Receptors in General
- 13 Peripheral Parts of the Somatosensory System
- 14 Central Parts of the Somatosensory System
- 15 Pain
- 16 The Visual System
- 17 The Auditory System
- 18 The Sense of Equilibrium
- 19 Olfaction and Taste
- Part Four Motor Systems
- 20 Motor Systems and Movements in General
- 21 The Peripheral Motor Neurons and Reflexes
- 22 The Motor Cortical Areas and Descending Pathways
- 23 The Basal Ganglia
- 24 The Cerebellum
- 25 Control of Eye Movements
- Part Five The Brain Stem and the Cranial Nerves
- 26 The Reticular Formation: Premotor Networks, Consciousness, and Sleep
- 27 The Cranial Nerves
- Part Six The Autonomic Nervous System
- 28 Visceral Efferent Neurons: The Sympathetic and Parasympathetic Divisions
- 29 Sensory Visceral Neurons and Visceral Reflexes
- 30 The Central Autonomic System: The Hypothalamus
- Part Seven Limbic Structures
- 31 The Amygdala and Other Neuronal Groups with Relation to Emotions
- 32 The Hippocampal Formation: Learning and Memory
- Part Eight The Cerebral Cortex
- 33 The Cerebral Cortex: Intrinsic Organization and Connections
- 34 Functions of the Neocortex
- Literature
- Index
