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Severe Valvular Disease 

Severe Valvular Disease
Chapter:
Severe Valvular Disease
Author(s):

Yafen Liang

, and Andrew Shaw

DOI:
10.1093/med/9780190226459.003.0008
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date: 19 September 2020

The pathophysiology of valvular diseases follows the fundamental principles of fluid and pressure dynamics. Alteration in any of the major components that determine forward flow can translate into a change in stroke volume, which in turn results in a change in cardiac output. The goal of managing severe valvular disease in the perioperative period is to maintain the forward flow required for end organ perfusion and minimize regurgitation. Accordingly, this chapter discusses the major principles involved in the pathophysiology of valve disease, as well as the perioperative assessment of disease severity and appropriate management based upon the type of lesion being encountered.

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