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Hypomagnesemia/Hypermagnesemia 

Hypomagnesemia/Hypermagnesemia
Chapter:
Hypomagnesemia/Hypermagnesemia
Author(s):

Aali Shah

DOI:
10.1093/med/9780190226459.003.0039
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date: 21 September 2020

Hypomagnesemia is a relatively common electrolyte abnormality that may produce little to no significant clinical manifestations in patients. Commonly used medications such as proton-pump inhibitors and antidepressants can cause magnesium deficiency. The primary cardiac effect of hypomagnesemia is a prolongation of the Q-T interval. It is exposure to other drugs in the perioperative period and physiologic changes caused by anesthesia and surgery that can further alter cardiac electrophysiology and lead to serious ventricular dysrhythmias. Hypermagnesemia is generally iatrogenic from excessive ingestion, renal failure, or therapeutic administration for preeclampsia. Adverse effects of hypermagnesemia include somnolence, muscle weakness, and slowing of cardiac conduction.

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