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Acid–Base and Electrolyte Disorders 

Acid–Base and Electrolyte Disorders
Acid–Base and Electrolyte Disorders

John A. Kellum

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date: 24 June 2021

An important principle in the management of electrolytes with CRRT is that “you get what you replace”. With hemofiltration all electro-lytes are freely removed (sieving coefficients near 1) and thus, over time and assuming no large intake or other losses, plasma concentra-tions will approach those of the replacement fluid. The rate at which electrolytes change is determined by how different the plasma con-centration is relative to that in the replacement fluid and the rate of fluid replacement deliv-ered.

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