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The Critically Ill Patient with Acute Kidney Injury 

The Critically Ill Patient with Acute Kidney Injury
Chapter:
The Critically Ill Patient with Acute Kidney Injury
Author(s):

Aditya Uppalapati

and John A. Kellum

DOI:
10.1093/med/9780190225537.003.0001
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date: 07 June 2020

The terms acute kidney injury (AKI) and acute renal failure (ARF) are not synonymous. While the term renal failure is best reserved for patients who have lost renal function to the point that life can no longer be sustained without intervention, AKI is used to describe the milder as well as severe forms of acute renal dysfunction in patients. Although the analogy is imperfect, the AKI–ARF relationship can be thought of as being similar to the relationship between acute coronary syndrome and ischemic heart failure. AKI is intended to describe the entire spectrum of disease from being relatively mild to severe. In contrast, renal failure is defined as renal function inadequate to clear the waste products of metabolism despite the absence of or correction of hemodynamic or mechanical causes.

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