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Chest Radiograph Screening for Lung Cancer: The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial 

Chest Radiograph Screening for Lung Cancer: The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial
Chapter:
Chest Radiograph Screening for Lung Cancer: The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial
Author(s):

Christoph I. Lee

DOI:
10.1093/med/9780190223700.003.0043
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date: 18 October 2019

This chapter, found in the cancer screening and management section of the book, provides a succinct synopsis of a key study examining the efficacy of chest radiography for screening for lung cancer. This summary outlines the study methodology and design, major results, limitations and criticisms, related studies and additional information, and clinical implications. Researchers reported that annual chest radiograph screening over a 4-year period did not decrease lung cancer mortality compared with usual care after 13 years of follow-up, and that chest x-rays are not an effective screening test for lung cancer. In addition to outlining the most salient features of the study, a clinical vignette and imaging example are included in order to provide relevant clinical context.

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