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Breast MRI for Women with Recently Diagnosed Breast Cancer: The American College of Radiology Imaging Network (ACRIN) Trial 6667 

Breast MRI for Women with Recently Diagnosed Breast Cancer: The American College of Radiology Imaging Network (ACRIN) Trial 6667
Chapter:
Breast MRI for Women with Recently Diagnosed Breast Cancer: The American College of Radiology Imaging Network (ACRIN) Trial 6667
Author(s):

Christoph I. Lee

DOI:
10.1093/med/9780190223700.003.0041
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date: 21 August 2019

This chapter, found in the cancer screening and management section of the book, provides a succinct synopsis of a key study examining the efficacy of breast magnetic resonance imaging for extent of disease evaluation among women with recently diagnosed breast cancer. This summary outlines the study methodology and design, major results, limitations and criticisms, related studies and additional information, and clinical implications. The study showed that breast MRI in newly diagnosed unilateral breast cancer patients can detect contralateral early-stage breast cancers missed by mammography and clinical breast examination. In addition, breast MRI has an extremely high negative predictive value, and may provide helpful information to women and physicians weighing the relative value of prophylactic contralateral mastectomy in the setting of unilateral breast cancer. In addition to outlining the most salient features of the study, a clinical vignette and imaging example are included in order to provide relevant clinical context.

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