Show Summary Details
Page of

Imaging Genetics 

Imaging Genetics
Imaging Genetics

Luanna Dixson

, Heike Tost

, and Andreas Meyer-Lindenberg

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2022. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 17 May 2022

Imaging genetics is the study of how modifications of the DNA sequence may manifest in altered brain structure, function, and biochemistry. This field has been made possible through the combined analysis of genotyping and neuroimaging data in the same individual. Imaging genetics has had an especially significant impact in the realm of psychiatry, where the identification of genetic variants associated with heritable “intermediate phenotypes” provides important clues about underlying molecular mechanisms. More recently, integration of information on biological pathways, protein interactions, epigenetic factors, and gene expression has provided a holistic framework for developing biologically driven hypotheses of gene effects in the brain. This chapter gives a historical perspective on the imaging genetics approach, outlines a few key examples, and speculates on future directions for this exciting discipline.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.