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Neuromodulation 

Neuromodulation
Chapter:
Neuromodulation
Author(s):

Bryan Covert

and Marc A. Huntoon

DOI:
10.1093/med/9780190217518.003.0010
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date: 23 October 2019

This chapter addresses the indications for and complications related to surgical, pharmacologic, and adjunctive neuromodulation therapy. Many forms of neuromodulation therapy find their inspiration from the landmark work by Melzack and Wall in 1965 that described the gate theory of pain. Fifty years later, technological and pharmaceutical progress leads the charge on this exciting field within pain medicine. As understanding of the generation, transmission, and interpretation of pain signaling expands, the options for interventional and medical therapy will surely follow suit. These advancements are a welcome addition as the aging population meets a medical community seeking to curb chronic opioid therapy. The questions in this chapter serve as a guide to the salient neuromodulation techniques, but an emphasis should be placed on the suggested readings in this chapter to develop a more thorough understanding of the topic and variety of techniques and pharmacotherapy not covered.

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