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Antiepileptic Drugs and Bone Health 

Antiepileptic Drugs and Bone Health
Chapter:
Antiepileptic Drugs and Bone Health
Author(s):

Ali A. Asadi-Pooya

and Michael R. Sperling

DOI:
10.1093/med/9780190214968.003.0029
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date: 23 October 2019

Patients taking antiepileptic drugs (AEDs) have higher rates of osteopenia, osteoporosis, and bone fractures than the general population. There are probably multiple causes of the increased rate of osteopenia and osteoporosis in epilepsy. Evidence suggests that AEDs may have negative effects on bone mineral density through a variety of mechanisms.

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