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Z. Crepeau Amy

and W. Britton Jeffrey

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date: 22 October 2019

Medications used in the treatment of nervous system disorders typically modulate neurotransmitter function or action potential propagation to result in alterations in neurologic function. This chapter begins with a discussion of principles of pharmacokinetics. Targets for drug action and a basis for understanding how medications exert their action are also discussed. Finally, disease-specific treatments are detailed.

Pharmacokinetic principles of neurologic medications are important to understand for the purposes of medication prescribing and ordering. Multiple routes of administration—intravenous, sublingual, intramuscular, subcutaneous, rectal, oral, and transdermal—are available for neurologic therapeutic agents.

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