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Introduction: Addiction from a Clinical Perspective 

Introduction: Addiction from a Clinical Perspective
Introduction: Addiction from a Clinical Perspective

Darius A. Rastegar

and Michael I. Fingerhood

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date: 01 April 2020

The use of a variety of psychoactive substances is common, and substance use disorders are responsible for a tremendous amount of preventable morbidity and mortality. Addiction is increasingly understood as a chronic disorder that involves a complex interplay of genetics, physiology, environment, and behavior. There are a range of terms and definitions used when describing these disorders. The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) provides criteria for “substance use disorders.” The other major source of terminology and diagnostic criteria is the World Health Organization’s International Classification of Diseases (ICD-10), which divides these into “harmful use” and “dependence syndrome.”

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