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Cerebrovascular Disease 

Cerebrovascular Disease
Chapter:
Cerebrovascular Disease
Author(s):

Andrea C. Adams

DOI:
10.1093/med/9780190206895.003.0011
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date: 15 October 2019

Transient ischemic attack (TIA) is an episode of focal neurologic dysfunction (brain, spinal cord, or retina) caused by ischemia. The clinical symptoms usually last less than 1 hour, and there is no evidence of acute infarction. Central nervous system infarction is defined as cell death attributable to ischemia with clinical, neuroimaging, and/or neuropathologic evidence of permanent injury. In the absence of imaging and pathologic evidence, clinical stroke is established by the persistence of symptoms for 24 hours. Silent infarction, discovered by imaging, has no known symptoms but remains an important issue in secondary stroke prevention.

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