Oxford Textbook of Medicine 6 edn – March 2022 update

March 24, 2022


The Oxford Textbook of Medicine had its latest update on 24th March 2022, featuring several new chapters (including COVID in Pregnancy) and section updates (Upper gastrointestinal endoscopy, Cardiac arrest, and Osteoporosis).

The COVID-19 Disease chapter has also been updated for a second time featuring updated classification of SARS-CoV-2 variants, new information on treatments including IL-6 receptor antagonists and anti-spike protein antibodies, alongside extended discussion of use of personal protective equipment (PPE) by healthcare workers. The updated COVID-19 Disease chapter is available free to read, here.


March 2022 updates:

8.5.30  COVID-19 Disease (updated 2nd time)

  • Updated classification of SARS-CoV-2 variants
  • Changing clinical presentation of new SARS-CoV-2 variants
  • New information on treatments including IL-6 receptor antagonists (e.g. tocilizumab, sarilimumab) and anti-spike protein antibodies (casirivimab, imdevimab)
  • Extended discussion of use of personal protective equipment (PPE) by healthcare workers
  • New information on benefits and risks of Covid-19 vaccination

14.22  COVID in Pregnancy (new chapter)

  • Completely new chapter.

15.3.2  Upper gastrointestinal endoscopy

  • A new section on Artificial Intelligence in Endoscopy has been included.

17.2  Cardiac arrest

  • A section has been added on COVID-19 and risks to the rescuer.
  • The advanced life support and post-resuscitation care algorithms have been replaced with 2021 versions.
  • The section on drugs has been updated to reflected recent the results of recent research
  • The section on extracorporeal CPR has been updated to reflect recent evidence.
  • Several domains in the post-resuscitation care section have been updated; in particular, the topic of temperature control. This section is now consistent with the 2021 European Resuscitation Council and European Society of Intensive Care Medicine Guidelines on Post-resuscitation Care.
  • The section on prognosis has been updated to reflect 2021 guidelines

20.4  Osteoporosis

  • Evidence from the MRC-SCOOP trial that systematic case finding in primary care leads to a reduction in hip fracture risk.
  • Introduction of treatment stratification by baseline fracture risk, according to recent IOF-ESCEO European recommendations.
  • Description of the anabolic agents, abaloparatide and romosozumab.