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MRI of Normal Brain Maturation: Preterm to Age 3 Years 

MRI of Normal Brain Maturation: Preterm to Age 3 Years
Chapter:
MRI of Normal Brain Maturation: Preterm to Age 3 Years
Source:
MRI Atlas of Pediatric Brain Maturation and Anatomy
Author(s):

Julie A. Matsumoto

, Cree M. Gaskin

, Derek Kreitel

, and S. Lowell Kahn

DOI:
10.1093/med/9780199796427.003.0001

Part I begins with a brief explanation of the process used for subject and image selection for the atlas, followed by short discussions on MR techniques and the basics of normal myelin and myelination. Observations on the practical assessment of myelination on MRI, in addition to recommendation on to how to best use myelination milestone references are included. Summaries of normal brain maturational changes in cortical folding and sulcation, the germinal matrix, white matter myelination, the basal ganglia and thalami, corpus callosum, ventricles and subarachnoid spaces, and the pituitary gland are provided for reference, grouped into three age ranges: preterm infant, term infant to 4 months of age, and 4 months to 3 years of age. A list of the timing of myelination signal on T1W and T2W images in numerous structures throughout the brain is provided in a detailed Table.

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