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Ovarian cancer and malignant bowel obstruction: Ovarian cancer and malignant bowel obstruction Expert commentary Iain McNeish Expert commentary Iain McNeish 

Ovarian cancer and malignant bowel obstruction: Ovarian cancer and malignant bowel obstruction Expert commentary Iain McNeish Expert commentary Iain McNeish
Chapter:
Ovarian cancer and malignant bowel obstruction: Expert commentary Iain McNeish
Source:
Challenging Concepts in Oncology
Author(s):

Caroline Chau

DOI:
10.1093/med/9780199688883.003.0006

Ovarian cancer typically presents at an advanced stage and requires a multidisciplinary approach in its management. This chapter covers the diagnosis, evidence-based treatments, and recent advances in ovarian cancer. The case study outlines the presentation and clinical course of a patient with advanced ovarian cancer. It summarizes the role of surgery, chemotherapy, and bevacizumab in first-line and in disease relapse settings, with reference to landmark trials such as ICON4, ICON7, OCEANS, and CALYPSO. Bowel obstruction is a common complication of this disease, seen in the acute oncology setting. Topical issues, such as routine germline BRCA1/2 testing and CA125 monitoring, have also been discussed.

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