Page of

Transformed follicular lymphoma: Transformed follicular lymphoma Expert commentary Andrew Davies Expert commentary Andrew Davies 

Transformed follicular lymphoma: Transformed follicular lymphoma Expert commentary Andrew Davies Expert commentary Andrew Davies
Chapter:
Transformed follicular lymphoma: Expert commentary Andrew Davies
Source:
Challenging Concepts in Oncology
Author(s):

Chern Siang Lee

DOI:
10.1093/med/9780199688883.003.0015

Follicular lymphoma is the commonest subtype of indolent non-Hodgkin’s lymphoma (NHL), with a steady rise in incidence over the last 40 years. It has a long clinical course, characterized by a progressing and regressing pattern in response to treatment, and is usually considered incurable. There is no consensus on optimal therapy, but the management strategy incorporates consideration of tumour characteristics and patient-related factors. The quality and duration of response typically decline with repeated treatments. This is particularly in the event of histological transformation to a more aggressive subtype of NHL such as diffuse large B-cell lymphoma. This case study illustrates the clinical approach to lymphoma in general and discusses in detail the management paradigm for indolent and transformed NHL.

Sign In

Copyright © 2020. All rights reserved.