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Sialorrhoea in Parkinson’s disease 

Sialorrhoea in Parkinson’s disease
Sialorrhoea in Parkinson’s disease
Non-motor Symptoms of Parkinson's Disease (2 ed.)

Julia Johnson

, Marian L. Evatt

, and K. Ray Chaudhuri


Sialorrhoea is a common symptom in neurodegenerative conditions such as Parkinson’s disease (PD). Sialorrhoea (also known as drooling) is an inability to control salivary secretion, which results in pooling of saliva in the oral cavity and causes a significant degree of social embarrassment and psychosocial difficulty for patients and their caregivers. It can also cause soiling of clothes and angular chelitis due to oral candidiasis. Posterior spillage involves saliva trickling into the pharynx; if not safely swallowed it may penetrate the airway and be aspirated. The literature contains limited data on sialorrhoea in PD. In a prevalence study of gastrointestinal symptoms in PD, abnormal salivation was reported as one of the most common gastrointestinal symptoms in patients with PD compared with controls. A significant proportion of patients with sialorrhoea also present with swallowing abnormalities. Dysphagia can lead to aspiration pneumonia, which is the major source of morbidity and mortality in PD.

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