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Biologics registries 

Biologics registries
Biologics registries
Oxford Textbook of Rheumatology (4 ed.)

David Isenberg

and Angela Zink

Previous versions of this chapter are available. To view earlier versions of this chapter view the full site here.

Double-blind controlled trials undertaken over the past two decades have established the short-term effectiveness and side-effect profile of biologic drugs for patients with rheumatoid arthritis and related diseases. However, the development of biologics registers to capture ’real-life experience’ and explore long-term effectiveness and complications is equally important. In this chapter, we demonstrate how these registers have identified long-term joint benefits, a reduction in cardiovascular mortality, reassurance concerning fears about cancer development, and a balanced view of the risk of infection.

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