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Biologics registries 

Biologics registries
Chapter:
Biologics registries
Source:
Oxford Textbook of Rheumatology (4 ed.)
Author(s):

David Isenberg

and Angela Zink

DOI:
10.1093/med/9780199642489.003.0034_update_002
Previous versions of this chapter are available. To view earlier versions of this chapter view the full site here.

Double-blind controlled trials undertaken over the past two decades have established the short-term effectiveness and side-effect profile of biologic drugs for patients with rheumatoid arthritis and related diseases. However, the development of biologics registers to capture ’real-life experience’ and explore long-term effectiveness and complications is equally important. In this chapter, we demonstrate how these registers have identified long-term joint benefits, a reduction in cardiovascular mortality, reassurance concerning fears about cancer development, and a balanced view of the risk of infection.

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