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Nephrogenic systemic fibrosis 

Nephrogenic systemic fibrosis
Chapter:
Nephrogenic systemic fibrosis
Source:
Oxford Textbook of Rheumatology (4 ed.)
Author(s):

Cate H. Orteu

DOI:
10.1093/med/9780199642489.003.0123

Nephrogenic systemic fibrosis (NSF) is a severe and disabling fibrosing condition of the skin and systemic organs. It occurs in patients with renal failure who have been exposed to gadolinum-based contrast agents (GBCAs). The development of NSF should be preventable if adequate precautions are taken in relation to GBCA exposure in susceptible patients. New cases should be reported to the European Medicines Agency and/or the United States Food and Drug Administration.

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