Homeostatic Control of Brain Function

Homeostatic Control of Brain Function

Detlev Boison and Susan A. Masino

Print publication date: Nov 2015

ISBN: 9780199322299

Publisher: Oxford University Press

Abstract

Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions – and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer’s or Parkinson’s are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include… • A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. • Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. • Incorporation of homeostatic therapies into existing basic and clinical research paradigms. • Extensive scientific basic and clinical research ranging from molecules to disorders. • Emerging practical information for improving homeostasis. • Examples of homeostatic therapies in preventing and delaying dysfunction.

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