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Bacterial, fungal, and parasitic infections of the liver 

Bacterial, fungal, and parasitic infections of the liver
Chapter:
Bacterial, fungal, and parasitic infections of the liver
Source:
Paediatric Gastroenterology, Hepatology and Nutrition (Oxford Specialist Handbooks in Paediatrics) (1 ed.)
Author(s):

R. Mark Beattie

, Anil Dhawan

, and John W.L. Puntis

DOI:
10.1093/med/9780198569862.003.0059

Bacterial sepsis 428

Spirochaetal infections 431

Rickettsial infections 432

Fungal infections 432

Parasitic infections 434

Granulomatous hepatitis 437

Infectious agents can affect the liver either via direct invasion or by release of toxins. The liver's dual blood supply renders it uniquely susceptible to infection, receiving blood from the intestinal tract via the hepatic portal system, and from the systemic circulation via the hepatic artery. Because of this unique perfusion, the liver is frequently exposed to systemic or intestinal infections or the mediators of toxaemia. The biliary tree provides a further conduit for gut bacteria or parasites to access the liver parenchyma....

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