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A Psychotic Break and Seizures 

A Psychotic Break and Seizures
A Psychotic Break and Seizures
Neurocritical Care (2 ed.)

Eelco F. M. Wijdicks

, Alejandro A. Rabinstein

, Sara E. Hocker

, and Jennifer E. Fugate


Autoimmune encephalitis has been recognized more often and classified into subtypes, although clinical characteristics overlap. Some distinguishing features are a psychotic break, autonomic dysfunction, seizures, depressed level of consciousness, or a new movement disorder. Patients with seizures due to autoimmune encephalitis are typically resistant to antiepileptic drugs, requiring multiple agents to abort the seizures. Early initiation of immunotherapy is directly related to outcomes in autoimmune encephalitis and perhaps even to control of refractory seizures. A practical approach is presented. Early treatment speeds recovery, reduces disability, and decreases relapses.

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